Investors & Media Institutional Ownership

Institutional Ownership

Top Holders

Holder Shares Held % O/S Share Change Filing Date
Roivant Sciences Ltd. 99,285,714 63.92 24,285,714 12/18/18
Deerfield Management Company, L.P. 10,000,000 6.44 10,000,000 12/18/18
Sphera Funds Management Ltd. 8,200,000 5.28 8,200,000 12/14/18
Renaissance Technologies LLC 2,091,700 1.35 788,100 9/30/18
BlackRock Institutional Trust Company, N.A. 1,422,048 0.92 169,190 9/30/18
IPL Advisers, LLC 1,207,958 0.78 -- 12/31/17
PRIMECAP Management Company 1,082,900 0.70 -- 9/30/18
Hudson Bay Capital Management LP 1,010,000 0.65 238,100 9/30/18
Adage Capital Management, L.P. 1,000,000 0.64 -- 9/30/18
Connor, Clark & Lunn Investment Management Ltd. 559,602 0.36 64,152 9/30/18

Top Holders: Mutual Funds

Fund Shares Held % O/S Share Change Filing Date
iShares NASDAQ Biotechnology ETF 1,371,648 0.88 -50,400 12/31/18
PRIMECAP Odyssey Aggressive Growth Fund 825,000 0.53 -- 9/30/18
Vanguard Health Care Index Fund 248,036 0.16 173,076 12/31/18
Vanguard US Opportunities Fund 193,900 0.12 -- 9/30/18
Virtus LifeSci Biotech Clinical Trials ETF 114,907 0.07 -9,549 11/30/18
ONELIFE FUND 80,000 0.05 80,000 12/31/17
DekaLux-BioTech 49,000 0.03 -1,000 6/30/18
ProShares Ultra Nasdaq Biotechnology 37,433 0.02 -9,094 12/31/18
BRJ US Mid and Small Cap Eq BIG Data Strategy(NH) 29,527 0.02 29,527 3/31/18
BRJ US Mid and Small Cap Eq BIG Data Strategy(H) 28,590 0.02 28,590 3/31/18

* Insider values reflect direct beneficial ownership.