Institutional Ownership

Top Holders

Holder Shares Held % O/S Share Change Filing Date
Roivant Sciences Ltd. 18,577,380 25.47 -- 7/31/21
Suvretta Capital Management, LLC 5,489,000 7.53 -- 6/30/21
Rubric Capital Management LP 3,000,000 4.11 499,582 6/30/21
Consonance Capital Management LP 2,969,987 4.07 -216,348 6/30/21
Opaleye Management Inc. 2,000,000 2.74 -- 6/30/21
The Vanguard Group, Inc. 1,948,262 2.67 920,972 6/30/21
Hudson Bay Capital Management LP 1,540,000 2.11 -60,000 6/30/21
SV Inflections GmbH 841,371 1.15 841,371 6/30/21
Two Sigma Investments, LP 667,493 0.92 -204,061 6/30/21
Medical Strategy GmbH 535,190 0.73 -- 5/31/21

Top Holders: Mutual Funds

Fund Shares Held % O/S Share Change Filing Date
Vanguard Total Stock Market Index Fund 1,283,882 1.76 -- 8/31/21
SV Inflections Fund FCP-RAIF 841,371 1.15 841,371 6/30/21
Vanguard Extended Market Index Fund 595,200 0.82 -- 8/31/21
MEDICAL BioHealth 313,897 0.43 -- 5/31/21
Bridgeway Ultra-Small Company Market Fund 298,300 0.41 -- 6/30/21
Fidelity Extended Market Index Fund 273,918 0.38 -- 7/31/21
APO Medical Opportunities 166,593 0.23 -- 3/31/21
iShares Micro-Cap ETF 97,263 0.13 -2,236 8/31/21
Franklin US Small Cap Equity Fund 80,000 0.11 80,000 6/30/21
Pengana High Conviction Equities Fund 65,438 0.09 -- 9/30/20

* Insider values reflect direct beneficial ownership.

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