Investors & Media Institutional Ownership

Institutional Ownership

Top Holders

Holder Shares Held % O/S Share Change Filing Date
Roivant Sciences Ltd. 99,285,714 63.84 24,285,714 12/18/18
Deerfield Management Company, L.P. 10,000,000 6.43 10,000,000 12/31/18
Sphera Funds Management Ltd. 8,200,000 5.27 8,200,000 12/31/18
Renaissance Technologies LLC 2,385,100 1.53 293,400 12/31/18
BlackRock Institutional Trust Company, N.A. 1,371,648 0.88 -50,400 12/31/18
Hudson Bay Capital Management LP 1,250,000 0.80 240,000 12/31/18
IPL Advisers, LLC 1,207,958 0.78 -- 12/31/17
PRIMECAP Management Company 1,057,600 0.68 -25,300 12/31/18
Monashee Investment Management, LLC 1,000,000 0.64 1,000,000 12/31/18
Adage Capital Management, L.P. 1,000,000 0.64 -- 12/31/18

Top Holders: Mutual Funds

Fund Shares Held % O/S Share Change Filing Date
iShares NASDAQ Biotechnology ETF 1,679,707 1.08 308,059 1/31/19
PRIMECAP Odyssey Aggressive Growth Fund 824,000 0.53 -1,000 12/31/18
Vanguard Health Care Index Fund 250,103 0.16 2,067 1/31/19
Vanguard US Opportunities Fund 185,900 0.12 -8,000 12/31/18
Fidelity NASDAQ Composite Index Fund 80,923 0.05 80,923 12/31/18
ONELIFE FUND 80,000 0.05 80,000 12/31/17
Invesco NASDAQ Biotech UCITS ETF 57,233 0.04 57,233 12/31/18
ATOMO SICAV - Mixed 50,000 0.03 50,000 12/31/18
DekaLux-BioTech 49,000 0.03 -1,000 6/30/18
ProShares Ultra Nasdaq Biotechnology 42,840 0.03 5,407 1/31/19

* Insider values reflect direct beneficial ownership.